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S0B5259PE Mouse Anti-Rat CD11b/c Antibody (S-R630)
產(chǎn)品型號:S0B5259
更新時間:2025-06-29
廠商性質(zhì):生產(chǎn)廠家
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CD11b and CD11c are two distinct integrin proteins that play crucial roles in the immune system. CD11b, also known as integrin alpha-M, is primarily expressed on myeloid cells such as macrophages and dendritic cells. It is involved in cell adhesion, migration, and immune cell activation. For example, CD11b ligation promotes pro-inflammatory macrophage signaling and regulates macrophage polarization. CD11c, on the other hand, is mainly found on dendritic cells and is associated with antigen presentation and T cell activation. CD11c+ CD11b+ dendritic cells have been shown to play an important role in the induction of T regulatory cells and the suppression of autoimmune diseases.
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