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S0B5262PE-Cy7 Rat Anti-Mouse/Human CD45R/B220 Antibody (S-R519)
產(chǎn)品型號:S0B5262
更新時間:2025-06-29
廠商性質(zhì):生產(chǎn)廠家
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CD45R/B220 is an isoform of the CD45 protein, a member of the protein tyrosine phosphatase (PTP) family, and serves as a critical regulator of T- and B-cell antigen receptor signaling. It is predominantly expressed on the surface of B cells, from early pro-B cells to mature and activated B cells, making it a commonly used pan-B cell marker in mice. Additionally, CD45R/B220 is also found on certain subsets of activated T cells, lymphokine-activated killer cells (LAK), NK cell progenitors, and T cells in mutant mice. This molecule plays a crucial role in lymphocyte development and antigen signaling, and its expression is regulated during different stages of B cell maturation.
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