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當前位置:首頁產品中心蛋白細胞因子S0A4067Mouse CXCL10/IP-10/CRG-2 Protein

Mouse CXCL10/IP-10/CRG-2 Protein
產品簡介:

Mouse CXCL10/IP-10/CRG-2 Protein

產品型號:S0A4067

更新時間:2025-07-02

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C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family. CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. CXCL9, CXCL10 and CXCL11 have proven to be valid biomarkers for the development of heart failure and left ventricular dysfunction, suggesting an underlining pathophysiological relation between levels of these chemokines and the development of adverse cardiac remodeling.

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