Brachyury Recombinant Rabbit mAb (SDT-1926-107)

產(chǎn)品型號：S0B2378

更新時間：2025-07-02

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

Brachyury protein is a transcription factor encoded by the TBXT gene, belonging to the T-box family of genes. It plays a crucial role in embryonic development, particularly in the formation and differentiation of the mesoderm and the notochord, which is the precursor of the spinal column. In adults, Brachyury is almost exclusively expressed in notochord-derived cells. Abnormal expression of Brachyury has been associated with certain cancers, such as chordoma, a malignant tumor that arises from residual notochordal cells. Additionally, it is involved in the epithelial-mesenchymal transition （EMT） in various carcinomas, promoting tumor invasion and metastasis.

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