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當前位置:首頁產(chǎn)品中心抗體/抗原偶聯(lián)抗體S0B1776Lamin A/C Recombinant Rabbit mAb (Alexa Fluor? 488 Conjugate) (SDT-R041)

Lamin A/C Recombinant Rabbit mAb (Alexa Fluor? 488 Conjugate) (SDT-R041)
產(chǎn)品簡介:

Lamin A/C Recombinant Rabbit mAb (Alexa Fluor? 488 Conjugate) (SDT-R041)

產(chǎn)品型號:S0B1776

更新時間:2025-07-01

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Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. Lamin A has a mass of about 74kDa while Lamin C is 65kDa. Mutations in the LMNA gene are associated with several serious human diseases, including Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease type 2B1, and Hutchinson-Gilford progeria syndrome.

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