O-Linked N-Acetylglucosamine Recombinant Rabbit mAb (S-R256)

產(chǎn)品型號：S0B0373

更新時間：2025-06-30

廠商性質(zhì)：生產(chǎn)廠家

訪問量：35

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

HA標簽重組兔單抗具有增強蛋白定位的能力

1h快速定量Total IgG

大鼠免疫球蛋白的結(jié)構(gòu)與功能研究

探索mRNA疫苗生產(chǎn)流程：酶產(chǎn)品的核心角色

產(chǎn)品介紹

O-GlcNAc （short for O-linked GlcNAc or O-linked β-N-acetylglucosamine） is a reversible enzymatic post-translational modification that is found on serine and threonine residues of nucleocytoplasmic proteins. The modification is characterized by a β-glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine （GlcNAc）. It has been suggested that apoptosis is regulated by O-GlcNAc. In various cancers, elevated O-GlcNAc levels have been reported to suppress apoptosis. Caspase-3, caspase-8, and caspase-9 have been reported to be modified by O-GlcNAc. Caspase-8 is modified near its cleavage/activation sites; O-GlcNAc modification may block caspase-8 cleavage and activation by steric hindrance. Pharmacological lowering of O-GlcNAc with 5S-GlcNAc accelerated caspase activation while pharmacological raising of O-GlcNAc with thiamet-G inhibited caspase activation.

上一個：S0B0141Vimentin Recombinant Rabbit mAb (Alexa Fluor? 488 Conjugate) (S-029-20)