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當前位置:首頁產品中心抗體/抗原病理/IHC抗體S0B2190Nectin-4 Recombinant Rabbit mAb (SDT-277-229)

Nectin-4 Recombinant Rabbit mAb (SDT-277-229)
產品簡介:

Nectin-4 Recombinant Rabbit mAb (SDT-277-229)

產品型號:S0B2190

更新時間:2025-06-30

廠商性質:生產廠家

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產品介紹

The Nectin cell adhesion molecule (Nectin) family members are Ca2+?independent immunoglobulin?like cellular adhesion molecules (including Nectins 1?4), involved in cell adhesion via homophilic/heterophilic interplay. In addition, the Nectin family plays a significant role in enhancing cellular viability and movement ability. In contrast to enrichment of Nectins 1?3 in normal tissues, Nectin?4 is particularly overexpressed in a number of tumor types, including breast, lung, urothelial, colorectal, pancreatic and ovarian cancer. Moreover, the upregulation of Nectin?4 is an independent biomarker for overall survival in numerous cancer types [PMID: 34664682].

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