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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2001Bcl-2 Recombinant Rabbit mAb (SDT-005-24)

Bcl-2 Recombinant Rabbit mAb (SDT-005-24)
產(chǎn)品簡介:

Bcl-2 Recombinant Rabbit mAb (SDT-005-24)

產(chǎn)品型號:S0B2001

更新時間:2025-06-30

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Bcl-2 (B-cell lymphoma 2) is the founding member of the Bcl-2 family of regulator proteins that regulate cell death (apoptosis), by either inhibiting (anti-apoptotic) or inducing (pro-apoptotic) apoptosis. It was the first apoptosis regulator identified in any organism. Bcl-2 is localized to the outer membrane of mitochondria, where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins. Damage to the Bcl-2 gene has been identified as a cause of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, and a possible cause of schizophrenia and autoimmunity. It is also a cause of resistance to cancer treatments.

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